Dafoe reprises his role from 's.
Filming occurred in the , , and neighborhoods in Queens.
She was hopeful that May's work as a community organizer would be featured in the film.
In February 2021, Holland said No Way Home was the final film under his contract but he hoped to continue playing Spider-Man in the future if asked.
Austen Goslin at conversely felt much of what had been rumored did not get revealed in the trailer, feeling that the rumors were either false or Marvel was still intending to keep them a secret.